DSS

DOI: 10.18129/B9.bioc.DSS  

Dispersion shrinkage for sequencing data

Bioconductor version: Release (3.16)

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu<hao.wu at emory.edu>, Hao Feng<hxf155 at case.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>, Hao Feng <hxf155 at case.edu>

Citation (from within R, enter citation("DSS")):

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DSS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DSS")

 

HTML R Script The DSS User's Guide
PDF   Reference Manual
Text   NEWS

Details

biocViews DNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, RNASeq, Sequencing, Software
Version 2.46.0
In Bioconductor since BioC 2.11 (R-2.15) (10.5 years)
License GPL
Depends R (>= 3.5.0), methods, Biobase, BiocParallel, bsseq, parallel
Imports utils, graphics, stats, splines
LinkingTo
Suggests BiocStyle, knitr, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me DeMixT
Imports Me borealis, DMRcate, kissDE, metaseqR2, MethCP, methylSig
Suggests Me biscuiteer, methrix, NanoMethViz, PROPER
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DSS_2.46.0.tar.gz
Windows Binary DSS_2.46.0.zip (64-bit only)
macOS Binary (x86_64) DSS_2.46.0.tgz
macOS Binary (arm64) DSS_2.46.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DSS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DSS
Bioc Package Browser https://code.bioconductor.org/browse/DSS/
Package Short Url https://bioconductor.org/packages/DSS/
Package Downloads Report Download Stats

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