LymphoSeq

Analyze high-throughput sequencing of T and B cell receptors


Bioconductor version: Release (3.20)

This R package analyzes high-throughput sequencing of T and B cell receptor complementarity determining region 3 (CDR3) sequences generated by Adaptive Biotechnologies' ImmunoSEQ assay. Its input comes from tab-separated value (.tsv) files exported from the ImmunoSEQ analyzer.

Author: David Coffey <dcoffey at fredhutch.org>

Maintainer: David Coffey <dcoffey at fredhutch.org>

Citation (from within R, enter citation("LymphoSeq")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("LymphoSeq")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("LymphoSeq")
Analysis of high-throughput sequencing of T and B cell receptors with LymphoSeq HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, MultipleSequenceAlignment, Sequencing, Software, TargetedResequencing, Technology
Version 1.34.0
In Bioconductor since BioC 3.3 (R-3.3) (8.5 years)
License Artistic-2.0
Depends R (>= 3.3), LymphoSeqDB
Imports data.table, plyr, dplyr, reshape, VennDiagram, ggplot2, ineq, RColorBrewer, circlize, grid, utils, stats, ggtree, msa, Biostrings, phangorn, stringdist, UpSetR
System Requirements
URL
See More
Suggests knitr, pheatmap, wordcloud, rmarkdown
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package LymphoSeq_1.34.0.tar.gz
Windows Binary (x86_64) LymphoSeq_1.34.0.zip (64-bit only)
macOS Binary (x86_64) LymphoSeq_1.34.0.tgz
macOS Binary (arm64) LymphoSeq_1.33.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/LymphoSeq
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/LymphoSeq
Bioc Package Browser https://code.bioconductor.org/browse/LymphoSeq/
Package Short Url https://bioconductor.org/packages/LymphoSeq/
Package Downloads Report Download Stats