RVS
Computes estimates of the probability of related individuals sharing a rare variant
DOI: 10.18129/B9.bioc.RVS
Bioconductor version: Release (3.20)
Rare Variant Sharing (RVS) implements tests of association and linkage between rare genetic variant genotypes and a dichotomous phenotype, e.g. a disease status, in family samples. The tests are based on probabilities of rare variant sharing by relatives under the null hypothesis of absence of linkage and association between the rare variants and the phenotype and apply to single variants or multiple variants in a region (e.g. gene-based test).
Author: Alexandre Bureau, Ingo Ruczinski, Samuel Younkin, Thomas Sherman
Maintainer: Alexandre Bureau <alexandre.bureau at fmed.ulaval.ca>
citation("RVS")):
Installation
To install this package, start R (version "4.4") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("RVS")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("RVS")| The RVS Package | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | ExomeSeq, Genetics, GenomeWideAssociation, ImmunoOncology, Software, VariantDetection, WholeGenome |
| Version | 1.28.0 |
| In Bioconductor since | BioC 3.6 (R-3.4) (7 years) |
| License | GPL-2 |
| Depends | R (>= 3.5.0) |
| Imports | GENLIB, gRain, snpStats, kinship2, methods, stats, utils, R.utils |
| System Requirements | |
| URL |
See More
| Suggests | knitr, testthat, rmarkdown, BiocStyle, VariantAnnotation |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | RVS_1.28.0.tar.gz |
| Windows Binary (x86_64) | RVS_1.28.0.zip |
| macOS Binary (x86_64) | RVS_1.28.0.tgz |
| macOS Binary (arm64) | RVS_1.27.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/RVS |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/RVS |
| Bioc Package Browser | https://code.bioconductor.org/browse/RVS/ |
| Package Short Url | https://bioconductor.org/packages/RVS/ |
| Package Downloads Report | Download Stats |